"The answer to Richard Dawkins' The Selfish Gene"

 

"no privileged level of causality"

 

"neo-Darwinian synthesis now known to be incompatible with the most recent discoveries"

 

 

"In addition to natural selection,

Darwin admits use and disuse as an important evolutionary mechanism"

 

"We are all feeling our way in the face of the extreme complexity of nature"

 

 

Quick download list:

 

Paton Lecture

Genes and Causation

Biophysics and Systems Biology

"Letter from Lamarck"

 

 

 

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    This page is where readers who wish to go deeper can find the ideas of The Music of Life sourced and developed further.

Published Lectures & articles (download pdfs)

Paton Lecture (ten principles of Systems Biology)

Principle of Biological Relativity

"There is no privileged level of causality in biological systems" (The Music of LIfe, page xii)  This lecture develops this principle in the context of general principles of systems biology.

Genes and Causation (relations between genes and phenotype)

Third principle: DNA is not the sole transmitter of inheritance.

"There are two components to molecular inheritance: the genome DNA, which can be viewed as digital information, and the cellular machinery, which can, perhaps by contrast, be viewed as analogue information."

Biophysics and Systems Biology (why Systems Biology is revolutionary)

Systems biology and evolution

"Central building blocks of the neo-Darwinian synthesis are now known to be incompatible with the most recent discoveries in molecular biology."

"Letter from Lamarck"

"Lamarckism"??

"There is a widespread perception that Darwin and Lamarck fought over this issue of the mechanisms of inheritance" (The Music of Life, page 99). This brief "Letter from Lamarck" explains why this perception is profoundly incorrect.

Video Lectures in English

Lecture in Dresden (ECCS 07) on videolectures.net

This lecture was given at a Conference on Complex systems in Dresden. It begins by noting that we do not yet really know what Systems Biology is. I agree with the following remark:

"You are probably running out of patience for some definition of systems biology. In any case, I do not think the explicit definition of systems biology should come from me but should await the words of the first great modern systems biologist. She or he is probably among us now." (Marc Kirschner, Harvard University, 2005, Cell, 121, 503-504).

We are all feeling our way in the face of the extreme complexity of nature and the daunting task of unraveling her secrets.

Interview in Dresden (ECCS 07) on videolectures.net

This interview followed the Dresden lecture and explains what the book and the lecture are about.

Lectures in Oxford  on www.pulse-project.org

These lectures on systems biology for a public audience were accompanied with music, one of them with the renowned classical guitarist, Christoph Denoth ( http://www.christophdenoth.com   )

Lectures in French 

Colloquium Jacques Morgenstern, INRIA, Sophia Antipolis, April 2007

Launch of La Musique de la Vie, Paris, January 2007

Congrès GIFRIC, Québec, May 2008

Concert Lectures

Presented with guitarist Christoph Denoth

 

 

 


The MUSIC of Life: Biology Beyond the Genome ©Denis Noble